The Mayo Clinic has conducted several studies which demonstrate the potential benefits of the hormone, which include, increase in the bone density, increase in the muscle mass, concurrent reduction of body fat and increased exercise capacity.

The most frequently quoted study on HGH, was published in the early 1990s, in the New England Journal of Medicine by Rudman and associates. The study was conducted on a small group of twelve elderly participants between the age of 61 to 80 years. The findings of the study, however resulted in an upheaval in the anti aging market and resulted in the launching of innumerable HGH products. The study indicated that the Gonadotropin could successfully reverse the signs of aging by almost ten to twenty years. The findings were based on a cohort study which extended for a period of approximately six months.

In a more elaborate study conducted at Palm Springs Life Extension Institute in collaboration with Department of Neurology, Medical college of Wisconsin, the findings were very similar. The study was conducted over 202 participants, being treated for Growth Hormone Deficiency. The hormone replacement therapy was found to be 100% beneficial to the participants. The major findings observed were : an increase in the bone density by about 1.5 – 2.5 % over a period of six months, along with loss of fat mass and a significant gain in lean muscle mass by 10 % each. Other benefits included: higher energy levels, increased exercise endurance and expanded exercise tolerance, an overall sense of well being, vigor, improved skin texture and tone, improved mental function, improved sexual capabilities, stimulation of hair growth and disappearance of wrinkles.

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